RNDr. Miroslav Machala, CSc.

2020

• Environmental six-ring polycyclic aromatic hydrocarbons are potent inducers of the AhR-dependent signaling in human cells

  VONDRÁČEK Jan PĚNČÍKOVÁ Kateřina CIGANEK Miroslav PIVNIČKA Jakub KARASOVÁ Martina HÝŽĎALOVÁ Martina STRAPÁČOVÁ Simona PÁLKOVÁ Lenka NEČA Jiří MATTHEWS Jason VOJTÍŠEK LOM Michal TOPINKA Jan MILCOVÁ Alena MACHALA Miroslav

  Article in Periodical

  Environmental Pollution, year: 2020, volume: 266, edition: November 2020, DOI

• Specific alterations of sphingolipid metabolism identified in EpCAM-positive cells isolated from human colon tumors

  PROCHÁZKOVÁ Jiřina SLAVIK Josef BOUCHAL Jan LEVKOVA Monika HUSKOVA Zlata EHRMANN Jiri OVESNÁ Petra KOLAR Zdenek SKALICKY Pavel STRAKOVA Nicol ZAPLETAL Ondrej KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, year: 2020, volume: 1865, edition: 9, DOI

2019

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Disrupts Control of Cell Proliferation and Apoptosis in a Human Model of Adult Liver Progenitors.

  SVOBODOVÁ Jana PROCHÁZKOVÁ Jiřina KABÁTKOVÁ Markéta KRKOŠKA Martin ŠMERDOVÁ Lenka LÍBALOVÁ Helena TOPINKA Jan KLÉMA Jiří KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  TOXICOLOGICAL SCIENCES, year: 2019, volume: 172, edition: 2, DOI

• Inhalation of ZnO Nanoparticles: Splice Junction Expression and Alternative Splicing in Mice

  RÖSSNER Pavel VRBOVÁ Kristýna STRAPÁČOVÁ Simona ROSSNEROVÁ Andrea AMBROZ Antonin BRZICOVA Tana LIBALOVÁ Helena JAVORKOVÁ Eliška KULICH Pavel VEČEŘA Zbyněk MIKUŠKA Pavel COUFALÍK Pavel KRUMAL Kamil ČAPKA Lukáš DOČEKAL Bohumil MORAVEC Pavel ŠERÝ Omar MÍŠEK Ivan FICTUM Petr FIŠER Karel MACHALA Miroslav TOPINKA Jan

  Article in Periodical

  Toxicological sciences, year: 2019, volume: 168, edition: 1, DOI

• n-3 Polyunsaturated fatty acids alter benzo[a]pyrene metabolism and genotoxicity in human colon epithelial cell models

  TYLICHOVÁ Zuzana NECA Jiri TOPINKA Jan MILCOVA Alena HOFMANOVÁ Jiřina KOZUBÍK Alois MACHALA Miroslav VONDRÁČEK Jan

  Article in Periodical

  Food and Chemical Toxicology, year: 2019, volume: 124, edition: FEB 2019, DOI

2018

• Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands

  PROCHÁZKOVÁ Jiřina STRAPÁČOVÁ Simona SVRŽKOVÁ Lucie ANDRYSÍK Zdeněk HYZDALOVA Martina HRUBÁ Eva PĚNČÍKOVÁ Kateřina LIBALOVA H TOPINKA J KLÉMA Jiří ESPINOSA JM VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  Toxicology Letters, year: 2018, volume: 292, DOI

• Atropisomers of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) exhibit stereoselective effects on activation of nuclear receptors in vitro

  PĚNČÍKOVÁ Kateřina BRENEROVÁ Petra SVRŽKOVÁ Lucie HRUBÁ Eva PÁLKOVÁ Lenka VONDRÁČEK Jan HANS-JOACHIM Lehmler MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, year: 2018

• Butyrate and docosahexaenoic acid interact in alterations of specific lipid classes in differentiating colon cancer cells.

  TYLICHOVÁ Zuzana SLAVÍK Josef CIGANEK Miroslav OVESNÁ Petra KRČMÁŘ Pavel STRAKOVÁ Nicol MACHALA Miroslav KOZUBÍK Alois HOFMANOVÁ Jiřina VONDRÁČEK Jan

  Article in Periodical

  JOURNAL OF CELLULAR BIOCHEMISTRY, year: 2018, volume: 119, edition: 6, DOI

• In vitro profiling of toxic effects of prominent environmental lower-chlorinated PCB congeners linked with endocrine disruption and tumor promotion

  PĚNČÍKOVÁ Kateřina SVRŽKOVÁ Lucie STRAPÁČOVÁ Simona NEČA Jiří BARTOŇKOVÁ Iveta DVOŘÁK Zdeněk HÝŽĎALOVÁ Martina PIVNIČKA Jakub PÁLKOVÁ Lenka HANS-JOACHIM Lehmler LI Xueshu VONDRÁČEK Jan MACHALA Miroslav

  Article in Periodical

  ENVIRONMENTAL POLLUTION, year: 2018

2017

• Butyrate alters expression of cytochrome P450 1A1 and metabolism of benzo[a] pyrene via its histone deacetylase activity in colon epithelial cell models

  ZAPLETAL Ondřej TYLICHOVÁ Zuzana NEČA Jiří KOHOUTEK Jiří MACHALA Miroslav MILCOVA A. POKORNA Michaela TOPINKA Jan MOYER M.P. HOFMANOVÁ Jiřina KOZUBÍK Alois VONDRÁČEK Jan

  Article in Periodical

  ARCHIVES OF TOXICOLOGY, year: 2017, volume: 91, edition: 5, DOI