Project information
Molecular identification and diagnostics of staphylococci causing nosocomial infections.
- Project Identification
- GA301/97/1192
- Project Period
- 1/1997 - 12/1999
- Investor / Pogramme / Project type
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Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
- Cooperating Organization
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Institute of Analytical Chemistry of the ASCR, v. v. i.
- Responsible person Ing. Karel Klepárník, CSc.
- Responsible person prof. MUDr. Václav Hájek, CSc.
The aim of the project is to make more accurate (on the basis of genome analysis) diagnostics of staphylococci causing nosocomial infections. By means of quantitative PFGE-macrorestriction analysis, hybridization techniques including ribotyping, PCR, and plasmid analysis, the genomic variability of multiresistant strains of S. aureus as well as strains of the coagulase-negative species, characterized of standard phenotypic tests, will be estimated. Genetic relationship among the strains found by DNA ana
Publications
Total number of publications: 14
2000
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Genomic relatedness of <I>Staphylococcus aureus</I> phages of the International Typing Set and detection of serogroup A, B, and F prophages in lysogenic strains
Canadian Journal of Microbiology, year: 2000, volume: 46, edition: 11
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Příprava specifických sond pro detekci profágů seroskupin A, B a F v lyzogenních kmenech Staphylococcus aureus
4th Workshop of Biochemists and Molecular Biologists. Biochemistry and molecular biology on the threshold of a new century, year: 2000
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Stanovení polymorfizmu genů pro tvorbu koagulázy, rezistenci k meticilinu a 16S-23S mezerníkových oblastí rDNA genů u Staphylococcus aureus metodou PCR
4th Workshop of Biochemists and Molecular Biologists. Biochemistry and molecular biology on the threshold of a new century, year: 2000
1999
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Complex genomic and phenotypic characterization of the related species <I>Staphylococcus carnosus</I> and <I>Staphylococcus piscifermentans</I>
International Journal of Systematic Bacteriology, year: 1999, volume: 49, edition: 3
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Genotypová variabilita kmenů Staphylococcus aureus rezistentních k oxacilinu
III. Pracovní setkání biochemiků a molekulárních biologů. Molekulární biologie a biochemie v humánní a veterinární medicíně., year: 1999
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Molecular typing and detection of toxin-producing strains Staphylococcus aureus
III. Pracovní setkání biochemiků a molekulárních biologů. Molekulární biologie a biochemie v humánní a veterinární medicíně., year: 1999
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Příprava DNA hybridizační sondy pro identifikaci kmenů druhu Staphylococcus aureus
III. Pracovní setkání biochemiků a molekulárních biologů. Molekulární biologie a biochemie v humánní a veterinární medicíně., year: 1999
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Příprava molekulární sondy pro identifikaci kmenů druhu Staphylococcus aureus
VIII. konference mladých mikrobiologů Tomáškovy dny '99, year: 1999
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Taxonomie stafylokoků
Remedia - Klinická mikrobiologie, year: 1999, volume: 3, edition: 2
1998
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Analysis of genomic DNA in TSST-1 positive strains of Staphylococcus aureus using PFGE and PCR methods
Scripta Medica (Brno), year: 1998, volume: 71, edition: 8