Project information
National institute for cancer research
(NÚVR)
- Project Identification
- LX22NPO5102
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Faculty of Medicine
- prof. RNDr. Ondřej Slabý, Ph.D.
- Mgr. Klára Baďurová
- MUDr. Viera Bajčiová, CSc.
- MUDr. Denisa Bakešová
- Mgr. Andrej Bešše, Dr. sc. nat.
- Mgr. Lenka Bešše, Ph.D.
- Ing. Eva Blahová, Ph.D.
- Mgr. Júlia Bohošová, Ph.D.
- Mgr. Michaela Bosáková, Ph.D.
- Mgr. Pavla Bouchalová, Ph.D.
- Mgr. Jana Bruknerová
- Ing. Daniel Buša
- Aleksandra Anna Czyrek, PhD
- PharmDr. Martin Čulen, Ph.D.
- Mgr. Adéla Dostálová
- prof. MUDr. Michael Doubek, Ph.D.
- Mgr. Barbara Dvořáčková, Ph.D.
- Mgr. Bohumil Fafílek, Ph.D.
- Mgr. Zuzana Feketová, Ph.D.
- Mgr. Alena Homolová, Ph.D.
- Mgr. Jan Hýl
- prof. RNDr. Mgr. Marie Jarošová, CSc.
- Mgr. Martina Jelínková
- Ing. Robin Jugas, Ph.D
- Mgr. Beáta Katrincsáková, Ph.D.
- RNDr. Ingrid Kováčová
- Mgr. Kateřina Koždoňová
- MUDr. Marie Kramárová
- RNDr. Pavel Krejčí, Ph.D.
- Helene Sorum Kristiansen
- MUDr. Zuzana Kuttnerová
- MUDr. Michal Kýr, Ph.D.
- Mgr. Petr Lapčík, Ph.D.
- Debora Ledahudcová
- RNDr. Jitka Malčíková, Ph.D.
- prof. MUDr. Jiří Mayer, CSc.
- MUDr. Tomáš Merta
- MUDr. Peter Múdry, Ph.D.
- Mgr. Veronika Navrkalová, Ph.D.
- Hana Novotná
- Mgr. Šárka Pavlová, Ph.D.
- Mgr. Lukáš Pečinka, Ph.D.
- Mgr. Karla Plevová, Ph.D.
- Barbora Podhajská
- Mgr. Petra Pokorná
- Helena Poláková
- MUDr. Kristýna Polášková, Ph.D.
- Mgr. Ing. Jakub Paweł Porc
- Mgr. Vendula Rašková, Ph.D.
- MUDr. Ondřej Rohleder
- doc. MUDr. Peter Rohoň, Ph.D.
- Ing. Mgr. Michaela Ručková
- Mgr. Tereza Růžičková
- Bc. Petra Sedláková
- Mgr. Lenka Sedlaříková, Ph.D.
- Mgr. Dagmar Smitalová
- Mgr. Bc. Karolína Smolková
- Mgr. Radim Sonnek
- Mgr. Kateřina Staňo Kozubík, Ph.D.
- Mgr. Kamila Stránská, Ph.D.
- Ing. Michaela Stroblová, Ph.D.
- Marcela Suránová
- Mgr. Hana Svozilová, Ph.D.
- Kateřina Svozilová
- doc. RNDr. Sabina Ševčíková, Ph.D.
- prof. MUDr. Jaroslav Štěrba, Ph.D.
- MUDr. Martin Štěrba
- MUDr. Silvie Šurková
- MUDr. Pavel Tinka
- MUDr. Terézia Tureková
- Dr. Suzanne Dawn Turner
- Mgr. Stjepan Uldrijan, CSc.
- Ing. Natália Vadovičová
- doc. RNDr. Petr Vaňhara, Ph.D.
- Mgr. Marek Večeřa
- MUDr. Klára Vejmělková, Ph.D.
- Mgr. Jana Vepřková
- Mgr. Bc. Monika Vlachová
- Mgr. Petra Vychytilová, Ph.D.
- MUDr. Danica Zapletalová, Ph.D.
- Miroslava Žítková, DiS.
- Other MU Faculty/Unit
-
Faculty of Science
- prof. Mgr. Vítězslav Bryja, Ph.D.
- doc. Mgr. David Bednář, Ph.D.
- doc. Mgr. Petr Beneš, Ph.D.
- Mgr. Karolína Bořánková, Ph.D.
- doc. Mgr. Pavel Bouchal, Ph.D.
- Mgr. Anežka Celá
- Mgr. Štěpán Čada
- Mgr. Kristína Gömöryová, Ph.D.
- Faraneh Haddadi
- RNDr. Vendula Hlaváčková Pospíchalová, Ph.D.
- Mgr. Jana Horáčková
- Mgr. Šárka Hrachovinová
- RNDr. Petr Chlapek, DiS., Ph.D.
- Mgr. Blanka Jančeková, Ph.D.
- Mgr. Pavlína Janovská, Ph.D.
- Mgr. Aneta Jarošková
- MUDr. Marta Ježová, Ph.D.
- Darja Klementová
- Mgr. Lucia Knopfová, Ph.D.
- Mgr. Jiří Kohoutek, Ph.D.
- Mgr. Petra Kompaníková
- Mgr. Lucia Krahulcová
- Mgr. Marek Kravec, Ph.D.
- Johana Marešová
- Stanislav Mazurenko, PhD
- Mgr. Jiřina Medalová, Ph.D.
- MUDr. Jan Mičan
- Mgr. Tereza Michalíková
- Mgr. Antónia Mikulová
- Mgr. Jarmila Navrátilová, Ph.D.
- doc. RNDr. Jakub Neradil, Ph.D.
- Ing. Zuzana Orlová
- Mgr. Martin Pavlíček
- Mgr. Hana Plešingerová, Ph.D.
- Mgr. Daniel Pluskal
- Mgr. Jana Pokludová
- Mgr. Petra Procházková
- Ing. Zuzana Prouzová, Ph.D.
- Mgr. Matěj Přikryl
- Viktor Pushkarov
- Bc. Janka Rakytová
- Mgr. Andrea Rousová
- Mgr. Kamila Říhová, Ph.D.
- Mgr. Eva Slabáková, Ph.D.
- Mgr. Stanislava Sladeček, Ph.D.
- Mgr. Karel Souček, Ph.D.
- Mgr. Lukáš Sourada
- Bc. Karolína Stöhrová
- Mgr. Bc. Alan Strunga
- Ing. Jan Šimoník
- RNDr. Jan Škoda, Ph.D.
- Dagmar Štodtová
- Ing. Jan Velecký
- Ing. Jan Verner, Ph.D.
- prof. RNDr. Renata Veselská, Ph.D., M.Sc.
- Mgr. Olga Vondálová Blanářová, Ph.D.
- Other MU Faculty/Unit
-
Central European Institute of Technology
- prof. RNDr. Šárka Pospíšilová, Ph.D.
- Mgr. Petra Babková
- Bc. et Bc. Erika Bajusová
- Nilanjan Banerjee, Ph.D.
- Mgr. Tereza Deissová
- Mgr. Lenka Dostálová
- Mgr. Kryštof Hlaváč
- Mgr. Lenka Humpolíková Adámková, Ph.D.
- Mgr. Libuše Janská, BA
- Bc. Jana Jedličková
- prof. MUDr. Zdeněk Kala, CSc.
- doc. MUDr. Tomáš Kazda, Ph.D.
- doc. MUDr. Igor Kiss, Ph.D., MBA
- Mgr. Filip Kledus
- Mgr. Kateřina Koželková
- Mgr. Adriana Ladungová
- Mgr. Táňa Macháčková, Ph.D.
- Ludmila Marková
- prof. MUDr. Mgr. Marek Mráz, Ph.D.
- Mgr. Jana Orlíčková
- Mgr. Karol Pál, Ph.D.
- Mgr. Hana Pálová, Ph.D.
- Barbora Petrlíková
- Mgr. Lenka Radová, Ph.D.
- Mgr. František Siegl
- prof. MUDr. Marek Svoboda, Ph.D.
- doc. Mgr. Jiří Šána, Ph.D.
- Mgr. Michal Šmída, Dr. rer. nat.
- Mgr. Jiří Štika, Ph.D.
- Mgr. Karolína Trachtová
- doc. Mgr. Lukáš Trantírek, Ph.D.
- RNDr. Silvie Trantírková, Ph.D.
- RNDr. Josef Večeřa, Ph.D.
- MVDr. Martina Vodinská
- Keywords
- oncology, cancer, national institute
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
- Responsible person Ing. Jiří Hašek, CSc.
- Responsible person Ing. Miroslava Anděrová, CSc.
- Responsible person Dr. Ing. Jiří Kotek
- Responsible person RNDr. Petr Dráber, DrSc.
- Responsible person prof. RNDr. Jan Konvalinka, CSc.
- Responsible person doc. Ing. Pavel Peterka, Ph.D.
- Responsible person prof. MUDr. Alexi Šedo, DrSc.
- Responsible person prof. MUDr. Martin Procházka, Ph.D.
- Responsible person prof. MUDr. Marek Svoboda, Ph.D.
The aim of the project is to create a nationwide network of collaborating workplaces conducting cutting-edge research in the field of oncology, which will take the form of a "National Institute". The reason for the creation of this authority is that research in oncology is currently not coordinated in any way and is fragmented across institutions.
The establishment of a National Institute for Cancer Research will bring together cutting-edge scientific expertise, tertiary education and relevant medical/health information resources. The thematic complementarity of the individual departments within the National Cancer Research Institute will allow for a comprehensive approach necessary for modern cancer research, concentrating on priority areas of medical education and research in the Czech Republic. Cancer research will thus become much more coordinated, strategic and efficient.
The great advantage of the National Institute is its transformative character, i.e. no new infrastructure will be built (an exception is the necessary construction of the GMP for somatic cell and gene therapy ATMP in pavilion C03), but the development and modernisation of existing capacities and human resources. This approach is highly efficient and financially sustainable in the long term.
The network of collaborating sites will consist of three Nodes (Prague Node - coordinator, Brno Node, Olomouc Node), which will cover the whole Czech Republic. The individual Nodes will be connected through a consortium agreement that defines the frameworks and rules of cooperation.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 253
2024
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STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
CELL REPORTS MEDICINE, year: 2024, volume: 5, edition: 3, DOI
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Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies
Cell Communication and Signaling, year: 2024, volume: 22, edition: 1, DOI
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Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug
Leukemia, year: 2024, volume: 38, edition: 8, DOI
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Structural Optimization of Azacryptands for Targeting Three-Way DNA Junctions
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, year: 2024, DOI
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Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma
Nature Communications, year: 2024, volume: 15, edition: 1, DOI
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The Genomic Landscape of Lymphomas Invading the Central Nervous System Inferred from Cell-Free DNA by Integrative NGS Analysis and the Diagnostic Benefit Compared to Flow Cytometry
Year: 2024, type: Conference abstract
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The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia
Leukemia, year: 2024, DOI
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Therapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL
HemaSphere, year: 2024, volume: 8, edition: 9, DOI
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Toxicity of external beam accelerated partial-breast irradiation (APBI) in adjuvant therapy of early-stage breast cancer: prospective randomized study
Radiation Oncology, year: 2024, volume: 19, edition: 1, DOI
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Transmembrane glycoprotein GPNMB is a candidate predictive biomarker and potentially a therapeutic target in metastatic renal cell carcinoma
Year: 2024, type: Conference abstract