Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 134
2024
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Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation
Open Biology, year: 2024, volume: 14, edition: 11, DOI
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Long-term zinc treatment alters the mechanical properties and metabolism of prostate cancer cells
Cancer Cell International, year: 2024, volume: 24, edition: 1, DOI
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Methods for Characterization of Biomolecular Interactions 2024
Year: 2024, type: Workshop
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MoaB2, a newly identified transcription factor, binds to σA in Mycobacterium smegmatis
Journal of Bacteriology, year: 2024, volume: 206, edition: 12, DOI
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Multimodal Microscopy Workshop: Probing the Triad of Structure, Mechanics, and Chemistry in Biological Systems 2024
Year: 2024, type: Workshop
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N-glycan profiling of tissue samples to aid breast cancer subtyping
Scientific Reports, year: 2024, volume: 14, edition: 1, DOI
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Novel, soluble 3-heteroaryl-substituted tanshinone mimics attenuate the inflammatory response in murine macrophages
Nature Scientific Reports, year: 2024, volume: 14, edition: 1, DOI
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Optimizing ChIRP-MS for Comprehensive Profiling of RNA-Protein Interactions in Arabidopsis thaliana: A Telomerase RNA Case Study
Plants, year: 2024, volume: 13, edition: 6, DOI
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para–Phenylenediamine Dimer as a Redox–Active Guest for Supramolecular Systems
Chemistry - A European Journal, year: 2024, volume: 30, edition: 25, DOI
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Phosphoric acid salts of amino acids as a source of oligopeptides on the early Earth
COMMUNICATIONS CHEMISTRY, year: 2024, volume: 7, edition: 1, DOI