Informace o projektu
Analýza biologicky významných molekulárních komplexů
- Kód projektu
- VS97032
- Období řešení
- 9/1997 - 12/2000
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Posílení výzkumu na vysokých školách
- Fakulta / Pracoviště MU
- Přírodovědecká fakulta
The aim of the project is to build a laboratory focused on the study of functionally important complexes of biomacromolecules, namely those of nucleic acids and proteins, which form so called genome architecture (telomeres, centromeres, A study of the genetic heterochromatin blocks, complexes of nuclear matrix, nucleosomes). Metabolism of genetic material (replication, transcription, recombination) proceeds at these complexes and is, therefore, significantly affectedby their properties. information in its nuclear context will determine the basis of education of our postgraduate students. During the next four years, the nucleoprotein complexes will be characterised, which form indispensable functional elements of eukaryotic chromosomes - the telomeres.
Publikace
Počet publikací: 34
1999
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Telomerase activity, telomere length and telomere structure in the dicot plant silene latifolia
Abstracts of telomeres and telomerase meeting, rok: 1999
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Telomeráza - aktivita a diagnostické použití u leukémií a solidních tumorů
Abstrakta 43. Studentské vědecké konference, rok: 1999
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Telomeric repeat organization-a comparative in situ study between man and rodent
Cytogenetics and Cell Genetics, rok: 1999, ročník: 86, vydání: 3-4
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Using detection of telomerase activityand expression in oncology diagnostics
The Wilhelm Bernhard's workshop 16th Internatonal Workshop on Cell Nucleus, rok: 1999
1998
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Developmental Control of Telomere Lengths and Telomerase Activity in Plants
The Plant Cell, rok: 1998, ročník: 10, vydání: 10
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Developmenthal control of telomere lengths and telomerase activity in plants
1st European workshop, rok: 1998
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DNA loop domains in a 1.4-Mb region around the human hprt gene mapped by cleavage mediated by nuclear matrix-associated topoisomerase II
Molecular and General Genetics, rok: 1998, ročník: 260, vydání: 5
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DNA methylation state of the CpG island at the Pa promoter within the bcr-abl locus followed in CML patients
Dynamic Organization of Nuclear Function, rok: 1998
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Dynamics of plant telomeres
15th International Workshop on the Cell Nucleus, rok: 1998
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Plant cells express telomerase activity upon transfer to callus culture, without extensively changing telomere lengths
Molecular and General Genetics, rok: 1998, ročník: 260, vydání: 5