Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonath Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 115
2023
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Composition of the commercial phage cocktail Bacteriofag Pseudomonas aeruginosa and its effect against health-care associated Pseudomonas aeruginosa strains from the Czech Republic
Year: 2023, type: Conference abstract
-
Conformational changes in baseplate required for genome delivery of S. aureus phage phi812
Year: 2023, type: Conference abstract
-
De novo design of peptides that form transmembrane barrel pores killing antibiotic resistant bacteria
Year: 2023, type: Conference abstract
-
DECIPHERING THE FUNCTIONALITY OF THE UNSTRUCTURED N-TERMINAL DOMAIN OF THE BACTERIAL INITIATION FACTOR 2
Year: 2023, type: Conference abstract
-
Designing spheroidal nanoparticles to induce membrane fusion of liposomes
Year: 2023, type: Conference abstract
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Direct detection methods for monitoring of therapeutic staphylococcal bacteriophages in clinical samples
Year: 2023, type: Conference abstract
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Důsledky vysoce supresivní léčby infekce HIV
Vnitrni Lekarstvi, year: 2023, volume: 69, edition: 5, DOI
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Effects of Dietary Zinc and/or an Herbal Mixture on Intestinal Microbiota and Barrier Integrity in Lambs
Agriculture, year: 2023, volume: 13, edition: 9, DOI
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Efficient Simulations of Solvent Asymmetry Across Lipid Membranes Using Flat-Bottom Restraints
Journal of Chemical Theory and Computation, year: 2023, volume: 19, edition: 18, DOI
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Elucidating the Mechanisms of Genome Release in Picornaviruses using Cryo-EM and Coarse-Grained Simulations
Year: 2023, type: Conference abstract