Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonath Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 115
2023
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Escheria Coli differs in virulence-associated genes between patients with colorectal neoplazma and healthy controls
Year: 2023, type: Appeared in Conference without Proceedings
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Escherichia coli from biopsies differ in virulence genes between patients with colorectal neoplasia and healthy controls
Frontiers in Microbiology, year: 2023, volume: 14, edition: April 2023, DOI
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Evolution of RNA viruses in trypanosomatids: new insights from the analysis of Sauroleishmania
Parasitology research, year: 2023, volume: 122, edition: 10, DOI
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Extraintestinal pathogenic Escherichia coli in camels: Characteristics and sources of infection
Year: 2023, type: Appeared in Conference without Proceedings
-
Genetic polymorphisms in innate immunity genes influence predisposition to tick-borne encephalitis
JOURNAL OF NEUROVIROLOGY, year: 2023, volume: 29, edition: 6, DOI
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Gut microbiota changes - dysbiotic senescence pattern in the context of viral suppression
Year: 2023, type: Conference abstract
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Characterisation of bacteriophages with therapeutic potential against healthcare-associated and multidrug-resistant Pseudomonas aeruginosa
Year: 2023, type: Conference abstract
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Characterisation of invisible conformation of domain 1.1 of σA factor of RNA polymerase from Bacillus subtilis
Year: 2023, type: Conference abstract
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Characterization of a transitionally occupied state and thermal unfolding of domain 1.1 of σ A factor of RNA polymerase from Bacillus subtilis
Proteins: Structure, Function and Bioinformatics, year: 2023, volume: 91, edition: 9, DOI
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Identification of phage defence systems targeting other viruses infecting bacterial hosts
Year: 2023, type: Conference abstract